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Dynamics of initiation, termination and reinitiation of DNA translocation by the motor protein EcoR124I

Type I restriction enzymes use two motors to translocate DNA before carrying out DNA cleavage. The motor function is accomplished by amino-acid motifs typical for superfamily 2 helicases, although DNA unwinding is not observed. Using a combination of extensive single-molecule magnetic tweezers and s...

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Bibliographic Details
Main Authors: Seidel, Ralf, Bloom, Joost G P, van Noort, John, Dutta, Christina F, Dekker, Nynke H, Firman, Keith, Szczelkun, Mark D, Dekker, Cees
Format: Artigo
Language:Inglês
Published: 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356320/
https://ncbi.nlm.nih.gov/pubmed/16292342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600881
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