The zinc-binding domain of Nna1 is required to prevent retinal photoreceptor loss and cerebellar ataxia in Purkinje cell degeneration (pcd) mice

The Purkinje cell degeneration (pcd) mouse undergoes retinal photoreceptor degeneration and Purkinje cell loss. Nna1 is postulated to be the causal gene for pcd. We show that a BAC containing the Nna1 gene rescues retinal photoreceptor loss and Purkinje cell degeneration, confirming that Nna1 loss-o...

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Bibliografiset tiedot
Päätekijät: Chakrabarti, Lisa, Eng, Jeremiah, Martinez, Refugio A., Jackson, Stephen, Huang, Jing, Possin, Daniel E., Sopher, Bryce L., La Spada, Albert R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602839/
https://ncbi.nlm.nih.gov/pubmed/18602413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2008.05.026
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