In vitro initial attachment of HIV-1 integrase to viral ends: control of the DNA specific interaction by the oligomerization state

HIV-1 integrase (IN) oligomerization and DNA recognition are crucial steps for the subsequent events of the integration reaction. Recent advances described the involvement of stable intermediary complexes including dimers and tetramers in the in vitro integration processes, but the initial attachmen...

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Библиографические подробности
Главные авторы: Lesbats, P., Métifiot, M., Calmels, C., Baranova, S., Nevinsky, G., Andreola, M. L., Parissi, V.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2008
Предметы:
Nucleic Acid Enzymes
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602759/
https://ncbi.nlm.nih.gov/pubmed/18987001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn796
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