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Structure of the parathyroid hormone receptor C-terminus bound to the G-protein dimer Gβ(1)γ(2)
A critical role of the Gβγ dimer in heterotrimeric G-protein signaling is to facilitate engagement and activation of the Gα subunit by cell-surface G protein-coupled receptors. However, high-resolution structural information of the connectivity between receptor and Gβγ has not previously been availa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2601695/ https://ncbi.nlm.nih.gov/pubmed/18611381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.04.010 |
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