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Structure of the parathyroid hormone receptor C-terminus bound to the G-protein dimer Gβ(1)γ(2)

A critical role of the Gβγ dimer in heterotrimeric G-protein signaling is to facilitate engagement and activation of the Gα subunit by cell-surface G protein-coupled receptors. However, high-resolution structural information of the connectivity between receptor and Gβγ has not previously been availa...

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Bibliografische gegevens
Hoofdauteurs: Johnston, Christopher A., Kimple, Adam J., Giguère, Patrick M., Siderovski, David P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601695/
https://ncbi.nlm.nih.gov/pubmed/18611381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.04.010
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