Wordt geladen...

Acidic Residues C-Terminal to the A2 Domain Facilitate Thrombin-Catalyzed Activation of Factor VIII

Factor VIII is activated by thrombin through proteolysis at Arg740, Arg372, and Arg1689. One region implicated in this exosite-dependent interaction is the factor VIII a2 segment (residues 711-740) separating the A2 and B domains. Residues 717-725 (DYYEDSYED) within this region consist of five acidi...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Newell, Jennifer L., Fay, Philip J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600807/
https://ncbi.nlm.nih.gov/pubmed/18642885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8007824
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!