2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer

Drug combination therapy is a key strategy to improve treatment efficacy and survival of cancer patients. In this study the effects of combining 2-methoxyoestradiol-3,17-O,O-bis-sulphamate (STX140), a microtubule disruptor, with 2-deoxy-D-glucose (2DG) were assessed in MCF-7 (breast) and LNCaP (pros...

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Detalhes bibliográficos
Main Authors: Tagg, S L C, Foster, P A, Leese, M P, Potter, B V L, Reed, M J, Purohit, A, Newman, S P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600694/
https://ncbi.nlm.nih.gov/pubmed/18985042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604752
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