Class III β-tubulin expression and in vitro resistance to microtubule targeting agents

BACKGROUND: Class III β-tubulin overexpression is a marker of resistance to microtubule disruptors in vitro, in vivo and in the clinic for many cancers, including breast cancer. The aims of this study were to develop a new model of class III β-tubulin expression, avoiding the toxicity associated wit...

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Hlavní autoři: Stengel, C, Newman, S P, Leese, M P, Potter, B V L, Reed, M J, Purohit, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816659/
https://ncbi.nlm.nih.gov/pubmed/20029418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605489
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