The therapeutic potential of a series of orally bioavailable anti-angiogenic microtubule disruptors as therapy for hormone-independent prostate and breast cancers

Therapies for hormone-independent prostate and breast cancer are limited, with the effectiveness of the taxanes compromised by toxicity, lack of oral bioavailability and drug resistance. This study aims to identify and characterise new microtubule disruptors, which may have improved efficacy relativ...

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Detalhes bibliográficos
Main Authors: Newman, S P, Foster, P A, Ho, Y T, Day, J M, Raobaikady, B, Kasprzyk, P G, Leese, M P, Potter, B V L, Reed, M J, Purohit, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360283/
https://ncbi.nlm.nih.gov/pubmed/18026194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604100
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