In vivo inhibition of angiogenesis by sulphamoylated derivatives of 2-methoxyoestradiol

Drugs that inhibit growth of tumours and their blood supply could have considerable therapeutic potential. 2-Methoxyoestradiol-3,17-O,O-bis-sulphamate (2-MeOE2bisMATE) has been shown to inhibit the proliferation of MCF-7 (ER+) breast cancer cells and angiogenesis in vitro. 2-MeOE2bisMATE and its ana...

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Detalhes bibliográficos
Main Authors: Chander, S K, Foster, P A, Leese, M P, Newman, S P, Potter, B V L, Purohit, A, Reed, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360171/
https://ncbi.nlm.nih.gov/pubmed/17426705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603727
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