Proteome-wide identification of proteins and their modifications with decreased ambiguities and improved false discovery rates using unique sequence tags

Identifying proteins correctly and with known levels of confidence remain as significant challenges for proteomics. Random or decoy peptide databases are increasingly being used to estimate the false discovery rate (FDR), e.g., from liquid chromatography-tandem mass spectrometry (LC-MS/MS) analyses...

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Main Authors: Shen, Yufeng, Tolić, Nikola, Hixson, Kim K., Purvine, Samuel O., Paša-Tolić, Ljiljana, Qian, Wei-Jun, Adkins, Joshua N., Moore, Ronald J., Smith, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600587/
https://ncbi.nlm.nih.gov/pubmed/18271604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac702328x
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