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Proteome-wide identification of proteins and their modifications with decreased ambiguities and improved false discovery rates using unique sequence tags

Identifying proteins correctly and with known levels of confidence remain as significant challenges for proteomics. Random or decoy peptide databases are increasingly being used to estimate the false discovery rate (FDR), e.g., from liquid chromatography-tandem mass spectrometry (LC-MS/MS) analyses...

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Detalhes bibliográficos
Main Authors: Shen, Yufeng, Tolić, Nikola, Hixson, Kim K., Purvine, Samuel O., Paša-Tolić, Ljiljana, Qian, Wei-Jun, Adkins, Joshua N., Moore, Ronald J., Smith, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600587/
https://ncbi.nlm.nih.gov/pubmed/18271604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac702328x
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