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Depletion of mitochondrial DNA in leucocytes harbouring the 3243A→G mtDNA mutation
BACKGROUND: The 3243A→G MTTL1 mutation is the most common heteroplasmic mitochondrial DNA (mtDNA) mutation associated with disease. Previous studies have shown that the percentage of mutated mtDNA decreases in blood as patients get older, but the mechanisms behind this remain unclear. OBJECTIVES AND...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMJ Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597915/ https://ncbi.nlm.nih.gov/pubmed/16950816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.043109 |
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