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Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives
Calcitriol (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-1α,3β,25-triol) is a powerful oncostatic form of vitamin D3 that is of limited clinical utility due to hypercalcemic (toxic) effects. Since the removal of the side chain reduces or eliminates the calcemic activity of vitamin D3, secosteroidal...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597640/ https://ncbi.nlm.nih.gov/pubmed/19037511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b809005j |
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