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Concerted Synthesis of a Spirobicyclic Type-VI β-Turn Mimic of Pro-Pro-Pro-NH(2)

[Image: see text] A highly concerted strategy for the synthesis of symmetrical type-VI β-turn mimics was formulated. A proof of concept is presented in the synthesis of a spirobicyclic peptidomimetic of Pro-Pro-Pro-NH(2); compound 6. The formation of an unusual adduct that was encountered in the pro...

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Détails bibliographiques
Auteurs principaux: Vartak, Ashish P., Johnson, Rodney L.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597554/
https://ncbi.nlm.nih.gov/pubmed/16494490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0600335
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