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To (TGF)β or not to (TGF)β: Fine-tuning of Smad Signaling Via Post-Translational Modifications
Smad proteins are key signal transducers for the TGF-β superfamily and are frequently inactivated in human cancers, yet the molecular basis of how their levels and activities are regulated remains unclear. Recent progress, discussed herein, illustrates the critical roles of Smad post-translational m...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597537/ https://ncbi.nlm.nih.gov/pubmed/18387785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.02.003 |
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