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To (TGF)β or not to (TGF)β: Fine-tuning of Smad Signaling Via Post-Translational Modifications

Smad proteins are key signal transducers for the TGF-β superfamily and are frequently inactivated in human cancers, yet the molecular basis of how their levels and activities are regulated remains unclear. Recent progress, discussed herein, illustrates the critical roles of Smad post-translational m...

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Bibliografske podrobnosti
Main Authors: Wrighton, Katharine H., Feng, Xin-Hua
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597537/
https://ncbi.nlm.nih.gov/pubmed/18387785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.02.003
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