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To (TGF)β or not to (TGF)β: Fine-tuning of Smad Signaling Via Post-Translational Modifications

Smad proteins are key signal transducers for the TGF-β superfamily and are frequently inactivated in human cancers, yet the molecular basis of how their levels and activities are regulated remains unclear. Recent progress, discussed herein, illustrates the critical roles of Smad post-translational m...

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Hlavní autoři: Wrighton, Katharine H., Feng, Xin-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597537/
https://ncbi.nlm.nih.gov/pubmed/18387785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.02.003
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