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HEI10 negatively regulates cell migration by inhibiting cyclin B/Cdk1 and other promotility proteins
HEI10 (CCNB1IP1) was first described as a RING-finger family ubiquitin ligase that regulates cell cycle by interacting with cyclin B and promoting its degradation. Subsequently, other studies suggested specific up-regulation of HEI10 in metastatic melanoma, and demonstrated direct interaction betwee...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597433/ https://ncbi.nlm.nih.gov/pubmed/17297447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210282 |
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