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Deregulation of HEF1 Impairs M-Phase Progression by Disrupting the RhoA Activation Cycle
The focal adhesion-associated signaling protein HEF1 undergoes a striking relocalization to the spindle at mitosis, but a function for HEF1 in mitotic signaling has not been demonstrated. We here report that overexpression of HEF1 leads to failure of cells to progress through cytokinesis, whereas de...
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| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society for Cell Biology
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1382310/ https://ncbi.nlm.nih.gov/pubmed/16394104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-03-0237 |
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