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A Novel Cas Family Member, HEPL, Regulates FAK and Cell Spreading

For over a decade, p130Cas/BCAR1, HEF1/NEDD9/Cas-L, and Efs/Sin have defined the Cas (Crk-associated substrate) scaffolding protein family. Cas proteins mediate integrin-dependent signals at focal adhesions, regulating cell invasion and survival; at least one family member, HEF1, regulates mitosis....

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Main Authors: Singh, Mahendra K., Dadke, Disha, Nicolas, Emmanuelle, Serebriiskii, Ilya G., Apostolou, Sinoula, Canutescu, Adrian, Egleston, Brian L., Golemis, Erica A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291417/
https://ncbi.nlm.nih.gov/pubmed/18256281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-09-0953
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