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POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies

The evolutionarily conserved human polymerase delta (POLD1) gene encodes the large p125 subunit which provides the essential catalytic activities of polymerase δ (Polδ), mediated by 5′–3′ DNA polymerase and 3′–5′ exonuclease moieties. POLD1 associates with three smaller subunits (POLD2, POLD3, POLD4...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Gene
Päätekijät: Nicolas, Emmanuelle, Golemis, Erica A., Arora, Sanjeevani
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier B.V. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969162/
https://ncbi.nlm.nih.gov/pubmed/27320729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2016.06.031
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