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Efficient tumor formation by single human melanoma cells

A fundamental question in cancer biology is whether cells with tumorigenic potential are common or rare within human cancers. Studies on diverse cancers, including melanoma, have indicated that only rare human cancer cells (0.1% to 0.0001%) have tumorigenic potential when transplanted into NOD/SCID...

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Autori principali: Quintana, Elsa, Shackleton, Mark, Sabel, Michael S., Fullen, Douglas R., Johnson, Timothy M., Morrison, Sean J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597380/
https://ncbi.nlm.nih.gov/pubmed/19052619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07567
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