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Efficient tumor formation by single human melanoma cells

A fundamental question in cancer biology is whether cells with tumorigenic potential are common or rare within human cancers. Studies on diverse cancers, including melanoma, have indicated that only rare human cancer cells (0.1% to 0.0001%) have tumorigenic potential when transplanted into NOD/SCID...

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Detalhes bibliográficos
Main Authors: Quintana, Elsa, Shackleton, Mark, Sabel, Michael S., Fullen, Douglas R., Johnson, Timothy M., Morrison, Sean J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597380/
https://ncbi.nlm.nih.gov/pubmed/19052619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07567
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