5-HT(4)-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles

BACKGROUND AND PURPOSE: The left ventricle in failing hearts becomes sensitive to 5-HT parallelled by appearance of functional G(s)-coupled 5-HT(4) receptors. Here, we have explored the regulatory functions of phosphodiesterases in the 5-HT(4) receptor-mediated functional effects in ventricular musc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Afzal, F, Andressen, K W, Mørk, H K, Aronsen, J M, Sjaastad, I, Dahl, C P, Skomedal, T, Levy, F O, Osnes, J-B, Qvigstad, E
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2008
विषय:
Research Papers
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597261/
https://ncbi.nlm.nih.gov/pubmed/18846035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.339
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