H(2)S-donating sildenafil (ACS6) inhibits superoxide formation and gp91(phox) expression in arterial endothelial cells: role of protein kinases A and G

BACKGROUND AND PURPOSE: Superoxide (O(2)(•−)), derived from nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, is associated with acute respiratory distress syndrome (ARDS). NADPH oxidase activity and expression are blocked by nitric oxide (NO) and sildenafil. As another gas, hydrogen sulp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Muzaffar, S, Jeremy, J Y, Sparatore, A, Del Soldato, P, Angelini, G D, Shukla, N
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2008
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597257/
https://ncbi.nlm.nih.gov/pubmed/18846041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.326
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