Mechanisms of TGFβ Inhibition of Lung Endodermal Morphogenesis: The role of TβRII, Smads, Nkx2.1 and Pten

Transforming growth factor-beta is a multifunctional growth factor with roles in normal development and disease pathogenesis. One such role is in inhibition of lung branching morphogenesis, although the precise mechanism remains unknown. In an explant model, all three TGFβ isoforms inhibited FGF10-i...

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Main Authors: Xing, Yiming, Li, Changgong, Hu, Lingyan, Tiozzo, Caterina, Li, Min, Chai, Yang, Bellusci, Saverio, Anderson, Stewart, Minoo, Parviz
格式: Artigo
語言:Inglês
出版: 2008
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597224/
https://ncbi.nlm.nih.gov/pubmed/18602626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.04.044
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