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Hic-5 Promotes the Hypertrophic Scar Myofibroblast Phenotype by Regulating the TGF-β1 Autocrine Loop
Following severe traumatic or thermal injury to the dermis, hypertrophic scars (HTS) often develop in humans. These scar fibroblasts (HTSF) retain the myofibroblast phenotype persistently, rather than transiently as in acute wounds. These pathogenic myofibroblasts constitutively express smooth muscl...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597160/ https://ncbi.nlm.nih.gov/pubmed/18401422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.90 |
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