Hic-5 Promotes the Hypertrophic Scar Myofibroblast Phenotype by Regulating the TGF-β1 Autocrine Loop

Following severe traumatic or thermal injury to the dermis, hypertrophic scars (HTS) often develop in humans. These scar fibroblasts (HTSF) retain the myofibroblast phenotype persistently, rather than transiently as in acute wounds. These pathogenic myofibroblasts constitutively express smooth muscl...

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Autori principali: Dabiri, Ganary, Tumbarello, David A., Turner, Christopher E., Van De Water, Livingston
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597160/
https://ncbi.nlm.nih.gov/pubmed/18401422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.90
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