Autocrine production of TGF-β1 promotes myofibroblastic differentiation of neonatal lung mesenchymal stem cells

We have isolated mesenchymal stem cells (MSCs) from tracheal aspirates of premature infants with respiratory distress. We examined the capacity of MSCs to differentiate into myofibroblasts, cells that participate in lung development, injury, and repair. Gene expression was measured by array, qPCR, i...

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Main Authors: Popova, Antonia P., Bozyk, Paul D., Goldsmith, Adam M., Linn, Marisa J., Lei, Jing, Bentley, J. Kelley, Hershenson, Marc B.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
Assuntos:
Translational Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886615/
https://ncbi.nlm.nih.gov/pubmed/20190033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00347.2009
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