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Autocrine production of TGF-β1 promotes myofibroblastic differentiation of neonatal lung mesenchymal stem cells

We have isolated mesenchymal stem cells (MSCs) from tracheal aspirates of premature infants with respiratory distress. We examined the capacity of MSCs to differentiate into myofibroblasts, cells that participate in lung development, injury, and repair. Gene expression was measured by array, qPCR, i...

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Hlavní autoři: Popova, Antonia P., Bozyk, Paul D., Goldsmith, Adam M., Linn, Marisa J., Lei, Jing, Bentley, J. Kelley, Hershenson, Marc B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886615/
https://ncbi.nlm.nih.gov/pubmed/20190033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00347.2009
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