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Autocrine production of TGF-β1 promotes myofibroblastic differentiation of neonatal lung mesenchymal stem cells

We have isolated mesenchymal stem cells (MSCs) from tracheal aspirates of premature infants with respiratory distress. We examined the capacity of MSCs to differentiate into myofibroblasts, cells that participate in lung development, injury, and repair. Gene expression was measured by array, qPCR, i...

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Detalhes bibliográficos
Main Authors: Popova, Antonia P., Bozyk, Paul D., Goldsmith, Adam M., Linn, Marisa J., Lei, Jing, Bentley, J. Kelley, Hershenson, Marc B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886615/
https://ncbi.nlm.nih.gov/pubmed/20190033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00347.2009
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