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Autocrine production of TGF-β1 promotes myofibroblastic differentiation of neonatal lung mesenchymal stem cells

We have isolated mesenchymal stem cells (MSCs) from tracheal aspirates of premature infants with respiratory distress. We examined the capacity of MSCs to differentiate into myofibroblasts, cells that participate in lung development, injury, and repair. Gene expression was measured by array, qPCR, i...

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Autors principals: Popova, Antonia P., Bozyk, Paul D., Goldsmith, Adam M., Linn, Marisa J., Lei, Jing, Bentley, J. Kelley, Hershenson, Marc B.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886615/
https://ncbi.nlm.nih.gov/pubmed/20190033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00347.2009
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