Autocrine production of TGF-β1 promotes myofibroblastic differentiation of neonatal lung mesenchymal stem cells

We have isolated mesenchymal stem cells (MSCs) from tracheal aspirates of premature infants with respiratory distress. We examined the capacity of MSCs to differentiate into myofibroblasts, cells that participate in lung development, injury, and repair. Gene expression was measured by array, qPCR, i...

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Autores principales: Popova, Antonia P., Bozyk, Paul D., Goldsmith, Adam M., Linn, Marisa J., Lei, Jing, Bentley, J. Kelley, Hershenson, Marc B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2010
Materias:
Translational Physiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886615/
https://ncbi.nlm.nih.gov/pubmed/20190033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00347.2009
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