Hic-5 promotes invadopodia formation and invasion during TGF-β–induced epithelial–mesenchymal transition

Transforming growth factor β (TGF-β)–stimulated epithelial–mesenchymal transition (EMT) is an important developmental process that has also been implicated in increased cell invasion and metastatic potential of cancer cells. Expression of the focal adhesion protein Hic-5 has been shown to be up-regu...

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Bibliographic Details
Main Authors: Pignatelli, Jeanine, Tumbarello, David A., Schmidt, Ronald P., Turner, Christopher E.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2012
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341156/
https://ncbi.nlm.nih.gov/pubmed/22529104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201108143
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