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Increased Hypothalamic Protein Tyrosine Phosphatase 1B Contributes to Leptin Resistance with Age

Animals at advanced ages exhibit a reduction in central leptin sensitivity. However, changes in growth, metabolism, and obesity risk occur much earlier in life, particularly during the transition from youth to middle age. To determine when initial decreases in central leptin sensitivity occur, lepti...

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Autors principals: Morrison, Christopher D., White, Christy L., Wang, Zhong, Lee, Seung-Yub, Lawrence, David S., Cefalu, William T., Zhang, Zhong-Yin, Gettys, Thomas W.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596872/
https://ncbi.nlm.nih.gov/pubmed/17038557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-0672
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