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Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho GTP-ase-dependent mechanism
Leptin, a profibrogenic cytokine plays an important role in the development of non alcoholic steatohepatitis. Leptin also regulates immune responses including macrophage phagocytic activity. Stellate cells are key elements in liver fibrogenesis, and previously we have demonstrated that phagocytosis...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596754/ https://ncbi.nlm.nih.gov/pubmed/18925608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22515 |
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