Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho GTP-ase-dependent mechanism

Leptin, a profibrogenic cytokine plays an important role in the development of non alcoholic steatohepatitis. Leptin also regulates immune responses including macrophage phagocytic activity. Stellate cells are key elements in liver fibrogenesis, and previously we have demonstrated that phagocytosis...

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Bibliographic Details
Main Authors: Jiang, Joy X., Mikami, Kenichiro, Shah, Vijay H., Torok, Natalie J
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596754/
https://ncbi.nlm.nih.gov/pubmed/18925608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22515
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