NOX2 plays a key role in stellate cell activation and liver fibrogenesis in vivo

BACKGROUND & AIMS: Hepatocyte apoptosis and activation of hepatic stellate cells (HSC) are critical events in fibrogenesis. We previously demonstrated that phagocytosis of apoptotic hepatocytes by HSC is profibrogenic. Based on this, as well as the observation that NADPH oxidase induction is cen...

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Detalhes bibliográficos
Main Authors: Jiang, Joy X., Venugopal, Senthil, Serizawa, Nobuko, Chen, Xiangling, Scott, Fiona, Li, Yong, Adamson, Roger, Devaraj, Sridevi, Shah, Vijay, Gershwin, M. Eric, Friedman, Scott L, Török, Natalie J
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949521/
https://ncbi.nlm.nih.gov/pubmed/20685364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.05.074
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