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Role of prostaglandin D(2) receptor DP as a suppressor of tumor hyperpermeability and angiogenesis in vivo
Although COX-dependent production of prostaglandins (PGs) is known to be crucial for tumor angiogenesis and growth, the role of PGD(2) remains virtually unknown. Here we show that PGD(2) receptor (DP) deficiency enhances tumor progression accompanied by abnormal vascular expansion. In tumors, angiog...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596745/ https://ncbi.nlm.nih.gov/pubmed/19060214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805171105 |
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