Učitavanje...

Acquired Resistance to EGFR Kinase Inhibitors Associated with a Novel T854A Mutation in a Patient with EGFR-Mutant Lung Adenocarcinoma

PURPOSE: Somatic mutations in the tyrosine kinase domain of EGFR are associated with sensitivity of lung adenocarcinomas to the EGFR tyrosine kinase inhibitors (TKIs), gefitinib and erlotinib. Acquired drug resistance is frequently associated with a secondary somatic mutation that leads to substitut...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Bean, James, Riely, Gregory J., Balak, Marissa, Marks, Jenifer L., Ladanyi, Marc, Miller, Vincent A., Pao, William
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596620/
https://ncbi.nlm.nih.gov/pubmed/19010870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0151
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!