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Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR TKI therapy in 155 patients with EGFR mutant Lung Cancers

PURPOSE: All patients with EGFR mutant lung cancers eventually develop acquired resistance to EGFR tyrosine kinase inhibitors (TKIs). Smaller series have identified various mechanisms of resistance, but systematic evaluation of a large number of patients to definitively establish the frequency of va...

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Detalhes bibliográficos
Main Authors: Yu, Helena A., Arcila, Maria E., Rekhtman, Natasha, Sima, Camelia S., Zakowski, Maureen F., Pao, William, Kris, Mark G., Miller, Vincent A., Ladanyi, Marc, Riely, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630270/
https://ncbi.nlm.nih.gov/pubmed/23470965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2246
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