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A Catalytic Role of Heparin within the Extracellular Matrix
We investigated the mechanism by which heparin enhances the binding of vascular endothelial growth factor (VEGF) to the extracellular matrix protein fibronectin. In contrast to other systems, where heparin acts as a protein scaffold, we found that heparin functions catalytically to modulate VEGF bin...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596404/ https://ncbi.nlm.nih.gov/pubmed/18845539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806692200 |
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