A Catalytic Role of Heparin within the Extracellular Matrix

We investigated the mechanism by which heparin enhances the binding of vascular endothelial growth factor (VEGF) to the extracellular matrix protein fibronectin. In contrast to other systems, where heparin acts as a protein scaffold, we found that heparin functions catalytically to modulate VEGF bin...

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Detaylı Bibliyografya
Asıl Yazarlar: Mitsi, Maria, Forsten-Williams, Kimberly, Gopalakrishnan, Manoj, Nugent, Matthew A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2008
Konular:
Glycobiology and Extracellular Matrices
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596404/
https://ncbi.nlm.nih.gov/pubmed/18845539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806692200
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