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A Catalytic Role of Heparin within the Extracellular Matrix

We investigated the mechanism by which heparin enhances the binding of vascular endothelial growth factor (VEGF) to the extracellular matrix protein fibronectin. In contrast to other systems, where heparin acts as a protein scaffold, we found that heparin functions catalytically to modulate VEGF bin...

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書誌詳細
主要な著者: Mitsi, Maria, Forsten-Williams, Kimberly, Gopalakrishnan, Manoj, Nugent, Matthew A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596404/
https://ncbi.nlm.nih.gov/pubmed/18845539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806692200
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