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Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers

Estrogen receptor (ER) dimerization is prerequisite for its activation of target gene transcription. Because the two forms of ER, ERα and ERβ, exhibit opposing functions in cell proliferation, the ability of ligands to induce ERα/β heterodimers vs. their respective homodimers is expected to have pro...

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Détails bibliographiques
Auteurs principaux: Powell, Emily, Xu, Wei
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596243/
https://ncbi.nlm.nih.gov/pubmed/19022902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807274105
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