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Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers

Estrogen receptor (ER) dimerization is prerequisite for its activation of target gene transcription. Because the two forms of ER, ERα and ERβ, exhibit opposing functions in cell proliferation, the ability of ligands to induce ERα/β heterodimers vs. their respective homodimers is expected to have pro...

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Detalhes bibliográficos
Main Authors: Powell, Emily, Xu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596243/
https://ncbi.nlm.nih.gov/pubmed/19022902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807274105
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