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A Computational-Based Approach to Identify Estrogen Receptor α/β Heterodimer Selective Ligands
The biologic effects of estrogens are transduced by two estrogen receptors (ERs), ERα and ERβ, which function in dimer forms. The ERα/α homodimer promotes and the ERβ/β inhibits estrogen-dependent growth of mammary epithelial cells; the functions of ERα/β heterodimers remain elusive. Using compounds...
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| Publicat a: | Mol Pharmacol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5801554/ https://ncbi.nlm.nih.gov/pubmed/29295894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.108696 |
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