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Identification of Estrogen Receptor Dimer Selective Ligands Reveals Growth-Inhibitory Effects on Cells That Co-Express ERα and ERβ

Estrogens play essential roles in the progression of mammary and prostatic diseases. The transcriptional effects of estrogens are transduced by two estrogen receptors, ERα and ERβ, which elicit opposing roles in regulating proliferation: ERα is proliferative while ERβ is anti-proliferative. Exogenou...

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Detalhes bibliográficos
Main Authors: Powell, Emily, Shanle, Erin, Brinkman, Ashley, Li, Jun, Keles, Sunduz, Wisinski, Kari B., Huang, Wei, Xu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274540/
https://ncbi.nlm.nih.gov/pubmed/22347418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030993
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