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Identification of Estrogen Receptor Dimer Selective Ligands Reveals Growth-Inhibitory Effects on Cells That Co-Express ERα and ERβ

Estrogens play essential roles in the progression of mammary and prostatic diseases. The transcriptional effects of estrogens are transduced by two estrogen receptors, ERα and ERβ, which elicit opposing roles in regulating proliferation: ERα is proliferative while ERβ is anti-proliferative. Exogenou...

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Библиографические подробности
Главные авторы: Powell, Emily, Shanle, Erin, Brinkman, Ashley, Li, Jun, Keles, Sunduz, Wisinski, Kari B., Huang, Wei, Xu, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274540/
https://ncbi.nlm.nih.gov/pubmed/22347418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030993
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