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Identification of Estrogen Receptor Dimer Selective Ligands Reveals Growth-Inhibitory Effects on Cells That Co-Express ERα and ERβ

Estrogens play essential roles in the progression of mammary and prostatic diseases. The transcriptional effects of estrogens are transduced by two estrogen receptors, ERα and ERβ, which elicit opposing roles in regulating proliferation: ERα is proliferative while ERβ is anti-proliferative. Exogenou...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Powell, Emily, Shanle, Erin, Brinkman, Ashley, Li, Jun, Keles, Sunduz, Wisinski, Kari B., Huang, Wei, Xu, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274540/
https://ncbi.nlm.nih.gov/pubmed/22347418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030993
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