Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice

Pancreatic ductal adenocarcinoma (PDAC) is believed to arise through a multistep model comprised of putative precursor lesions known as pancreatic intraepithelial neoplasia (PanIN). Recent genetically engineered mouse models of PDAC demonstrate a comparable morphologic spectrum of murine PanIN (mPan...

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Bibliografski detalji
Glavni autori: Habbe, Nils, Shi, Guanglu, Meguid, Robert A., Fendrich, Volker, Esni, Farzad, Chen, Huiping, Feldmann, Georg, Stoffers, Doris A., Konieczny, Stephen F., Leach, Steven D., Maitra, Anirban
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596215/
https://ncbi.nlm.nih.gov/pubmed/19028870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810097105
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