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Acinar Cells Contribute to the Molecular Heterogeneity of Pancreatic Intraepithelial Neoplasia

A number of studies have shown that pancreatic ductal adenocarcinoma develops through precursor lesions termed pancreatic intraepithelial neoplasia (PanIN). PanINs are thought to initiate in the small ducts of the pancreas through activating mutations in the KRAS proto-oncogene. What remains unanswe...

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Detalhes bibliográficos
Main Authors: Zhu, Liqin, Shi, Guanglu, Schmidt, C. Max., Hruban, Ralph H., Konieczny, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941579/
https://ncbi.nlm.nih.gov/pubmed/17591971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061176
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