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Whole chromosome instability and cancer: a complex relationship
Although chromosome mis-segregation is a hallmark of cancer cells, its genetic basis and role in malignant transformation remain poorly understood. In recent years, several mouse models have been generated that harbor gene defects that perturb high-fidelity chromosome segregation. Analysis of these...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2594012/ https://ncbi.nlm.nih.gov/pubmed/18675487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2008.07.002 |
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