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Synthesis of 2-epi-Amphidinolide E: An Unexpected and Highly Selective C(2) Inversion During an Esterification Reaction

A synthesis of 2-epi-amphidinolide E (1) has been accomplished via an unexpected and highly diastereoselective C(2) stereochemical inversion during the modified Yamaguchi esterification of alcohol 4b and Fe(CO)(3)-complexed dienoic acid 7.

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Hlavní autoři: Va, Porino, Roush, William R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593877/
https://ncbi.nlm.nih.gov/pubmed/17217291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0628098
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