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Unified Synthesis of C(19)–C(26) Subunits of Amphidinolides B(1), B(2), and B(3) by Exploiting Unexpected Stereochemical Differences in Crimmins’ and Evans’ Aldol Reactions

The efficient synthesis of the C(19)–C(26) subunit of amphidinolide B(1) and B(2) has been completed using a boron-mediated aldol reaction. The synthesis of the C(19)–C(26) subunit of amphidinolide B(3) has also been accomplished through an unexpected anti aldol reaction using a titanium-mediated pr...

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Main Authors: Zhang, Wei, Carter, Rich G., Yokochi, Alexandre F. T.
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430272/
https://ncbi.nlm.nih.gov/pubmed/15049660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo035829l
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