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Structure of the wild-type human BCL6 POZ domain
BCL6 is a transcriptional repressor that is overexpressed in diffuse large B-cell lymphoma and follicular lymphoma. The N-terminal POZ domain of BCL6 interacts with transcriptional corepressors and targeting these associations is a promising therapeutic strategy. Previous structural studies of the B...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
International Union of Crystallography
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593701/ https://ncbi.nlm.nih.gov/pubmed/19052359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108036063 |
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