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Structure of the human Nac1 POZ domain

Nac1 is a POZ-domain transcription factor that is involved in the self-renewal of embryonic stem cells. It is overexpressed in ovarian serous carcinoma and targeting the interactions of its POZ domain is a potential therapeutic strategy. Nac1 lacks a zinc-finger DNA-binding domain and thereby differ...

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Bibliografiska uppgifter
Huvudupphovsmän: Stead, Mark A., Carr, Stephen B., Wright, Stephanie C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: International Union of Crystallography 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675581/
https://ncbi.nlm.nih.gov/pubmed/19407373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109012214
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